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Updated: Aug 19, 2026

In Vivo Assay for Detection of Antigen-specific T-cell Cytolytic Function Using a Vaccination Model
Published on: November 28, 2017
[A comparison of two antigens for Montenegro skin test]
Héctor Dardo Romero1, Aluízio Prata, Mário León Silva-Vergara
1Disciplina de Doenças Infecciosas e Parasitárias da Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG.
Abstract:
Intradermal reactions were performed in 399 individuals by using, simultaneously, the antigen produced by both the Universidade Federal de Minas Gerais and Fundação Instituto Oswaldo Cruz. Each of these antigens was manufactured with promastigotes of Leishmania (L) amazonensis (IFLA/BR/67/PH8). The Fundação Oswaldo Cruz antigen caused a larger number of positive reactions. Discordant reactions occurred in 22% of the individuals.

