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Published on: February 2, 2015
The widened frontal subarachnoid space. A CT comparative study between macrocephalic, microcephalic, and
1Department of Radiology, Hamad Medical Corporation, Doha, Qatar.
Insights
Frontal subarachnoid space widening in children is often not linked to macrocephaly. This finding suggests it may be a normal developmental variation, not necessarily external hydrocephalus.
Area of Science:
- Pediatric Radiology
- Neuroimaging
- Developmental Pediatrics
Background:
- Frontal subarachnoid space widening is a radiologic finding observed in pediatric computed tomographic (CT) scans.
- This finding has been anecdotally associated with macrocephaly in children.
Purpose of the Study:
- To retrospectively evaluate the association between frontal subarachnoid space widening and macrocephaly in pediatric patients.
- To determine if clinical and radiologic characteristics differ between macrocephalic and normocephalic/microcephalic children with this finding.
Main Methods:
- Retrospective review of CT head scans from 67 infants and children with frontal subarachnoid space widening over a 5-year period.
- Analysis of patient cohorts based on head circumference (macrocephalic, normocephalic, microcephalic).
- Comparison of clinical and radiologic features across these groups.
Main Results:
- Macrocephaly was present in only 22.3% of the studied patients.
- No significant differences were found in clinical or radiologic characteristics between macrocephalic and normocephalic/microcephalic children with frontal subarachnoid space widening.
- The association between this radiologic sign and macrocephaly may be overemphasized.
Conclusions:
- Frontal subarachnoid space widening in children might represent a normal developmental variation with transient cerebrospinal fluid accumulation.
- The term "external hydrocephalus" may be inappropriate without significant ventricular enlargement or signs of increased intracranial pressure.
- This finding warrants a re-evaluation of its diagnostic significance in the absence of other pathological indicators.
Abstract:
The computed tomographic scans of the heads of 67 infants and children with frontal subarachnoid space widening seen during a 5-year period were retrospectively studied. Only 22.3% of patients had macrocephaly. Comparison of the clinical and radiologic characteristics of subarachnoid widening in macrocephalic children and in normocephalic or microcephalic children showed no significant differences. It is concluded that undue emphasis has been laid on the association between this radiologic sign and macrocephaly. Widening of the subarachnoid space in children may be a variation of normal development of brain whereby there is a transient accumulation of cerebrospinal fluid in the frontal region. The term "external hydrocephalus" may therefore be inappropriate in the absence of significant ventricular widening and clinical signs of raised intracranial pressure.
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