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Updated: Aug 19, 2026

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Published on: February 27, 2015
[Effect of cancer cells on the spectra of serums]
Xiang-hong Ge1, Yuan-li Zhao, Feng-qiu Zhang
1School of Physical Engineering, Zhengzhou University, Zhengzhou 450052, China.
Abstract:
This article studied the different effects on the spectra of serums by adding different amount of cancer cells into serum, and gives the comparison between CNE cells' serum spectra and Hela' as well as that between abnormal serums and normal ones. Experiment results showed that the intensity of the absorption spectra and the fluorescence spectra exhibits a trend that it increases with the decrease in the cancer cells' number, while begins to drop when it goes up to a certain extent. The intensity of the normal serums' spectra is obviously higher than that of the abnormal one. It is concluded that the changes in the intensity of fluorescence spectra' show that the cancer cells restrain the vibration of some group in the normal serums, and the absorption spectra' reveal that the cancer cells prevent the casein from absorbing light.
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