Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endogamy, consanguinity and community disease profiles.

A H Bittles1

  • 1Centre for Human Genetics, Edith Cowan University, 100 Joondalup Drive, Perth, WA 6027, Australia. a.bittles@ecu.edu.au

Community Genetics
|March 16, 2005
PubMed
Summary

Community endogamy

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Population structure and inherited genetic disorders in the Bedouin of the Negev.

Journal of community genetics·2019
Same author

Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide.

Journal of community genetics·2018
Same author

Isonymic analysis of post-famine relationships in the Ards Peninsula, N.E. Ireland: Effects of geographical and politico-religious boundaries.

American journal of human biology : the official journal of the Human Biology Council·2017
Same author

CONSANGUINITY, GENETICS AND DEFINITIONS OF KINSHIP IN THE UK PAKISTANI POPULATION.

Journal of biosocial science·2015
Same author

Genetics and global healthcare.

The journal of the Royal College of Physicians of Edinburgh·2013
Same author

The triple challenges associated with age-related comorbidities in Down syndrome.

Journal of intellectual disability research : JIDR·2013

Area of Science:

  • Population genetics
  • Human genetics
  • Genetic epidemiology

Background:

  • Consanguineous marriage is a known factor in genetic disorders.
  • Community endogamy's impact on homozygosity and disease is under-investigated.
  • Understanding population genetics is crucial during the epidemiological transition.

Purpose of the Study:

  • To highlight the under-investigated role of community endogamy in population genetics.
  • To emphasize the growing importance of genetic disorders, especially adult-onset diseases.
  • To underscore the need for incorporating intercommunity genetic variation in research.

Main Methods:

  • This study is a review and theoretical analysis.
  • It synthesizes existing literature on consanguinity and endogamy.
  • It discusses implications for genetic disorder prevalence and research design.

Main Results:

  • Community endogamy, like consanguinity, can increase homozygosity.
  • Genetic factors in adult-onset diseases will become more apparent.
  • Intercommunity variation is critical for pharmacogenetics and forensic genetics.

Conclusions:

  • Further research into community endogamy's genetic impact is essential.
  • Accurate population-genetic understanding is vital for public health and personalized medicine.
  • Study designs must account for genetic variation between communities.

Related Experiment Videos