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Updated: Aug 19, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
[The relationship between hypertension and cerebral hemodynamic scores of vascular function accumulative]
Jiu-yi Huang1, Gui-qing Wang, Yi-feng Cao
1Shanghai Institute of Cerebral Vascular Disease Prevention and Cure, Shanghai 201318, China.
Insights
Hypertension significantly lowers cerebral vascular function scores, especially with longer disease duration and higher blood pressure levels. This highlights the impact of hypertension on cerebrovascular health.
Area of Science:
- Cardiovascular Science
- Neurology
- Medical Research
Context:
- Hypertension is a prevalent condition affecting vascular health globally.
- Cerebral vascular health is crucial for cognitive function and overall well-being.
- Understanding the impact of hypertension on cerebrovascular function is essential for preventative strategies.
Purpose:
- To investigate the relationship between hypertension and cerebral vascular hemodynamic indexes (CVHI).
- To assess how hypertension history and blood pressure levels influence cerebral vascular function scores.
- To quantify the decline in cerebral vascular function associated with hypertension.
Summary:
- A cohort study of 18,512 participants analyzed blood pressure and CVHI data.
- Hypertension was associated with a significant 13.3-point decrease in cerebral vascular function scores.
- Score decline correlated with hypertension duration and elevated systolic/diastolic blood pressure.
Impact:
- Findings demonstrate a clear link between hypertension and reduced cerebral vascular function.
- Elevated blood pressure (≥140/95 mmHg) significantly impairs cerebrovascular function.
- This research underscores the importance of hypertension management for preserving brain vascular health.
Objective:
To probe into the relationship between hypertension and hemodynamic score of cerebral vascular accumulative function by though studying the history of hypertension and level of blood pressure.
Methods:
The database of blood pressure and cerebral vascular hemodynamic indexes (CVHI) were from baseline data and measurement in a cohort. 18,512 participants who met the included criteria were enlisted in the study. The function scores were estimated using uniform methods according to CVHI. Participants were grouped by age, years of having hypertension and level of blood pressure. Differences of the function score between different groups were compared.
Results:
The function score in hypertension group was significantly lower than that of normal tension group, which decreased by 13.3 points. Within 5 years of hypertension history, the function score decreased as course of hypertension prolonged. The same trend was found between the score and level of both systolic and diastolic blood pressure. When systolic blood pressure elevated to 140 mmHg or diastolic blood pressure elevated to 95 mmHg, the function score was below 75 points.
Conclusion:
There were significant relationship between decrease of the function scores and medical history, course of hypertension as well as level of blood pressure.
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