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[Decision making in non resectable head and neck tumours].
1Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde/Plastische Operationen, Universität Leipzig. andreas.dietz@medizin.uni-leipzig.de
Laryngo- Rhino- Otologie
|March 17, 2005
Summary
For advanced head and neck cancers deemed non-resectable, simultaneous chemoradiation therapy is the recommended treatment. Salvage surgery may be used for residual neck disease, with chemotherapy for palliative care.
Area of Science:
- Oncology
- Head and Neck Surgery
Background:
- Advanced squamous cell carcinomas of the oral cavity, oro-, hypopharynx, and larynx are often non-resectable.
- Treatment decisions involve complex morphological, social, and ethical considerations.
Purpose of the Study:
- To outline decision-making processes for non-resectable head and neck tumors.
- To review therapeutic options including chemoradiation, brachytherapy, and chemotherapy.
Main Methods:
- Review of current therapeutic strategies for non-resectable head and neck cancers.
- Discussion of chemotherapy agents and brachytherapy in specific scenarios.
Main Results:
- Simultaneous chemoradiation therapy is recommended for non-resectable cases.
- Brachytherapy is an alternative for selected cases to avoid extensive surgery.
- Salvage surgery is common for residual neck disease post-chemoradiation.
Conclusions:
- Therapeutic decisions for non-resectable head and neck tumors require a multidisciplinary approach.
- Chemoradiation is a primary treatment, with salvage surgery and palliative chemotherapy as important adjuncts.