Related Experiment Video
Updated: Aug 19, 2026

A Neonatal Intravenous Transplant Model for Assessment of Early-Life Immune Activities Against Cancer Cells
Published on: June 26, 2026
Pediatric hematology and oncology in Iran
1Department of Pediatric Hematology and Oncology, Shohada Medical Center, Shaheed Beheshti University of Medical Sciences, Tajrish-Tehran, Iran. alebouyehm@yahoo.com
Insights
Pediatric hematology and oncology services in Iran have expanded to meet the needs of children with blood disorders and cancers. Advances include improved care for beta-thalassemia and hemophilia, and standardized childhood cancer treatment.
Area of Science:
- Pediatric Hematology and Oncology
- Public Health Initiatives
- Chronic Disease Management
Background:
- Rapid expansion of Pediatric Hematology and Oncology (PHO) field necessitates optimized services.
- Increasing demand for comprehensive medical care for children with blood diseases and malignancies.
- Need to address prevalence and clinical importance of these conditions in Iran.
Purpose of the Study:
- To outline the expansion and optimization of PHO services in Iran.
- To detail the management strategies for major beta-thalassemia and hemophilia.
- To describe the treatment protocols for childhood malignancies and available advanced therapies like Bone Marrow Transplantation (BMT).
Main Methods:
- Expansion and optimization of PHO services by trained specialists and improved facilities.
- Implementation of premarital screening and legal abortion for major beta-thalassemia.
- Supervision and treatment of hemophiliacs through specialized care centers.
- Regular screening for transfusion-related complications and viral diseases (HBV, HCV, HIV).
- Adoption of international protocols for childhood malignancies treatment.
- Public awareness campaigns and establishment of support groups and NGOs.
- Foundation of the Iranian Society of Pediatric Hematology and Oncology (ISPHO).
Main Results:
- Significant expansion and optimization of PHO services across Iran.
- Standardized care for major beta-thalassemia (transfusion, chelation, screening) and hemophilia.
- Comparable results in childhood malignancy treatment using international protocols.
- Availability of Bone Marrow Transplantation (BMT) for selected cases.
- Increased public awareness and establishment of patient support networks.
- Consolidation of resources through the ISPHO.
Conclusions:
- Collaborative studies and strategic planning are crucial for improving medical services, especially in underdeveloped regions.
- Addressing national health challenges requires a scientifically based approach to service provision.
Unlabelled:
Pediatric hematology and oncology (PHO) is a rapidly expandingfield. It has been our goal to meet the needs and increasing demands for comprehensive medical care of children suffering from chronic blood diseases and malignancies. In the past decade we have been able expand and optimize the PHO services throughout Iran, in general and in respect to their prevalence and clinical importance, by trained pediatric hematologist-oncologists, pediatric surgeons and improved para clinical facilities. Major beta-thalassemics receive blood transfusion and chelation therapy according to the current standards mostly at regional blood banks centers. To curb major beta-thalassemia a premarital screening program has been enacted and abortion has been legitimized if major thalassemia is diagnosed by CVS. Hemophiliacs are supervised and treated as indicated by Iranian Hemophilia Comprehensive Care Centers (IHCCC). Screening for transfusion related complications and transmitted viral diseases (HBV, HCV and HIV) in both cohorts are carried out in regular intervals and necessary management will be then carried out as indicated at respective specialized units. Childhood malignancies are treated according to protocols adopted from accredited institutions in the USA and Europe, with almost comparable results. BMT is available for selected patients with beta-thalassemia or malignancies. By going to public we have been able to rise general awareness about chronic blood diseases and childhood malignancies and have initiated establishment of parents groups and formation of NGOs to support these children and their families. Foundation of Iranian Society of Pediatric Hamatology and Oncology (ISPHO) in the year 2000 has been another step forward to consolidate and coordinate the available manpower and facilities.
Conclusion:
By evaluation of the country's main problems and shortcomings and conduction of collaborative studies and operation planning one will succeed to get the expected feedback and scientifically based approach to provide medical services to far reaching underdeveloped regions.
Related Concept Videos
Regulation of Hematopoietic Stem Cells
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
