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Clinical spectrum in hospitalized children with echovirus type 13 infection

Ken-Ichiro Kobayashi1, Tsunekazu Haruta, Masaru Kubota

  • 1Department of Pediatrics, Kobe City General Hospital, Kobe 650-0046, Japan. ckg-kobayashi@rio.odn.ne.jp

Pediatrics International : Official Journal of the Japan Pediatric Society
|March 18, 2005
PubMed

Insights

Echovirus type 13 (E13) infection presents with varied symptoms in children, often differing by age. This study highlights non-specific febrile illness, gastroenteritis, bronchitis, and aseptic meningitis as common E13 manifestations.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Clinical Epidemiology

Background:

  • Echovirus type 13 (E13) is a significant viral pathogen.
  • Understanding the clinical presentation of E13 is crucial for timely diagnosis and management in pediatric populations.

Purpose of the Study:

  • To investigate the diverse clinical spectrum of echovirus type 13 infections.
  • To analyze the age-specific manifestations of E13 in hospitalized children.

Main Methods:

  • Prospective viral surveillance conducted from April to August 2002.
  • Inclusion of hospitalized children aged 10 days to 14 years, regardless of symptoms.
  • Review of medical records for laboratory-confirmed E13 cases.

Main Results:

  • 41 patients analyzed; median age 3.4 years, 30% under 1 year.
  • Common clinical features included aseptic meningitis (16), non-specific febrile illness (9), gastroenteritis (7), and bronchitis (7).
  • Age-specific symptoms observed: febrile illness in infants, enterocolitis/bronchitis in 1-6 year olds, and aseptic meningitis in older children.

Conclusions:

  • E13 infection symptoms are age-dependent in hospitalized children.
  • Idiopathic thrombocytopenic purpura was an observed complication in two patients with E13 infection.
Abstract

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