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Updated: Aug 19, 2026

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
Published on: June 18, 2020
[New therapeutic strategies in ANCA-associated systemic vasculitis]
1Service d'immunologie et allergie, CHUV, Rue du Bugnon 46, 1011 Lausanne. floriana.lurati@chuv.hospvd.ch
Abstract:
High-dose corticosteroids in combination with cytotoxic drugs are universally accepted as the initial treatment in ANCA-associated vasculitis. Cyclophosphamide is the most effective cytotoxic drug and is used in more severe cases. Because of short- and long-term side-effects, novel therapies have been tested. New prospects for the treatment of vasculitis include sequential chemotherapy (e.g. cyclophosphamide followed by azathioprine or cyclophosphamide followed by methotrexate) and/or novel immunosuppressive agents (e.g. mycophenolate mofetil, anti-TNF-alpha).
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