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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Age-related aspects of balloon angioplasty for postsurgical aortic recoarctation
Gabriella Agnoletti1, Philipp Bonhoeffer, Adele Borghi
1Service de Cardiologie, Hopital Necker Enfant Malades, Paris, France. gabriella.agnoletti@nck.ap-hop-paris.fr
Insights
Balloon angioplasty effectively treats aortic recoarctation in children. While younger children may have higher rates of hypertension, the procedure
Area of Science:
- Pediatric Cardiology
- Interventional Cardiology
- Vascular Surgery
Background:
- Aortic recoarctation, a narrowing of the aorta, can occur after surgery.
- Balloon angioplasty is a common treatment for aortic recoarctation.
- Concerns exist regarding the safety and efficacy of balloon angioplasty in very young children.
Purpose of the Study:
- To investigate age-related outcomes of balloon angioplasty for postsurgical aortic recoarctation.
- To compare the risks and success rates in children younger than 1 year versus those older than 1 year.
Main Methods:
- Retrospective analysis of 58 children undergoing balloon angioplasty for postsurgical recoarctation.
- Patients were divided into two groups: younger than 1 year (n=30) and older than 1 year (n=28).
- Outcomes assessed included recoarctation frequency, presence of hypertension, procedural success, residual gradient, and complications.
Main Results:
- Recoarctation was more common in children with congenital heart defects.
- Younger children (<1 year) had higher rates of pre-existing and post-procedure systolic hypertension.
- Balloon angioplasty demonstrated similar success rates (86-87%) and complication profiles across age groups, with no increased risk for infants.
Conclusions:
- Balloon angioplasty is a safe and effective treatment for aortic recoarctation in children of all ages.
- Younger children with recoarctation are more prone to hypertension, requiring careful monitoring.
- The procedure's success is not age-dependent, but vigilance for potential complications is warranted.
Abstract:
Balloon angioplasty is now the elective technique for relief of aortic recoarctation, since it has low mortality, low morbidity, and good results at follow-up. Some concern exists concerning the possible increased risk in young children. To investigate such age-related aspects, we examined 58 children undergoing consecutive balloon angioplasty for postsurgical recoarctation. Of the children, 30 were younger and 28 older than 1 year. Recoarctation was more frequent with ventricular septal defect or other cardiac anomalies (p < 0.001). Systolic hypertension was present in 70% of children aged less than 1 year, but in only 32% of those older than 1 year (p < 0.001). The initial gradient was inversely related with the age at dilation (r = -0.28, p < 0.05), and correlated with systolic blood pressure (r = 0.81, p < 0.01). The procedure was successful in 87% of children older than, and 86% of those under 1 year. Age was not related with residual gradient, nor with the percentage increase of diameter of the site of stenosis. After balloon angioplasty, systolic hypertension was still present in 37% of children younger than 1 year, and in 25% of those older than 1 year (p < 0.05). Three complications occurred in children younger than 1 year, and 6 in those older (p < 0.05). Our results show, first, that recoarctation occurs earlier in the setting of complex disease, second that children suffering recoarctation at a younger age are more likely to be hypertensive, either before or after balloon angioplasty, third, that balloon angioplasty has the same rate of success in children below or above the age of one year, although the procedure still carries a not negligible risk. Finally, the procedure does not carry a higher risk for those children below the age of 1 year.
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