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Updated: Aug 19, 2026

Visualization of Germinosomes and the Inner Membrane in Bacillus subtilis Spores
Published on: April 15, 2019
Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of
1Department of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, Farmington, CT 06030-3305, USA. setlow@nso2.uchc.edu
Abstract:
Germination of Bacillus subtilis spores via the GerA nutrient receptor was suppressed by GerAC lacking the diacylglycerylated cysteine essential for receptor function. Overexpression of the C protein of the GerB nutrient receptor also suppressed the function of both the GerA receptor and a variant GerB receptor, GerB*. These findings suggest that GerAC and GerBC interact with their respective A and B proteins in GerA or GerB receptors and that GerBC potentially interacts with GerAA-GerAB. However, GerAC did not appear to interact with GerBA-GerBB.
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