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Published on: February 6, 2021
Endophthalmitis associated with the Ahmed glaucoma valve implant
A A Al-Torbak1, S Al-Shahwan, I Al-Jadaan
1FRCS, Department of Ophthalmology, King Khaled Eye Specialist Hospital, PO Box 7191 Riyadh 11462, Saudi Arabia. atorbaq@health.net.sa
Insights
Endophthalmitis after glaucoma drainage implant (GDI) surgery is rare but more frequent in children. Conjunctival erosion over the implant tube is a key risk factor, necessitating prompt surgical revision.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Infectious Disease
Background:
- Glaucoma drainage implants (GDIs) are used to manage refractory glaucoma.
- Endophthalmitis is a serious intraocular infection that can lead to vision loss.
- Understanding endophthalmitis risk after GDI surgery is crucial for patient management.
Purpose of the Study:
- To determine the incidence of endophthalmitis following glaucoma drainage implant (GDI) surgery.
- To identify risk factors, clinical presentation, and treatment outcomes of post-GDI endophthalmitis.
- To evaluate the role of conjunctival erosion in the development of endophthalmitis.
Main Methods:
- Retrospective review of medical records of patients who developed endophthalmitis after Ahmed glaucoma valve (AGV) implantation.
- Database search identified patients undergoing GDI surgery between January 1994 and November 2003.
- Statistical analysis, including multiple regression, was used to identify risk factors.
Main Results:
- The rate of endophthalmitis following GDI surgery was 1.7% (9 out of 542 eyes).
- Endophthalmitis occurred five times more frequently in children than adults.
- Conjunctival erosion over the AGV tube was a significant risk factor, present in 6 of 9 cases.
Conclusions:
- Endophthalmitis is a rare but significant complication of GDI surgery, particularly in pediatric patients.
- Conjunctival dehiscence overlying the GDI tube is a major risk factor for developing endophthalmitis.
- Early surgical intervention for exposed GDI tubes is recommended to prevent endophthalmitis.
Aim:
To investigate the rate, risk factors, clinical course, and treatment outcomes of endophthalmitis following glaucoma drainage implant (GDI) surgery.
Methods:
A computerised relational database search was conducted to identify all patients who were implanted with Ahmed glaucoma valve (AGV) and developed endophthalmitis following surgery at the King Khaled Eye Specialist Hospital in Riyadh, Saudi Arabia, between 1 January 1994 and 30 November 2003. Only medical records of the patients who developed endophthalmitis were retrospectively reviewed.
Results:
542 eyes of 505 patients who were on active follow up were included in the study. Endophthalmitis developed in nine (1.7%) eyes; the rate was five times higher in children than in adults. Delayed endophthalmitis (developed 6 weeks after surgery) occurred in eight of nine eyes. Conjunctival erosion overlying the AGV tube was present in six of nine eyes. Common organisms isolated in the vitreous included Haemophilus influenzae and Streptococcus species. Multiple regression analysis revealed that younger age and conjunctival erosion over the tube were significant risk factors associated with endophthalmitis.
Conclusion:
Endophthalmitis is a rare complication of GDI surgery that appears to be more common in children. Conjunctival dehiscence over the GDI tube seems to represent a major risk factor for endophthalmitis. Prompt surgical revision of an exposed GDI tube is highly recommended.
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