[Clinical characteristic of adynamic bone]
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Updated: Aug 19, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model
Published on: September 8, 2023
1Shintokorozawa-Seiwa Hospital.
Abstract:
Suppression on both bone formation and absorption is a characteristic histology of adynamic (or aplastic) bone (ABD). This new entity of renal osteodystrophy started to appear in bone biopsy findings in 1983. Most significant etiology of adynamic bone is relatively lower serum PTH level. Any study has failed to demonstrate that ABD would increase the incidence of bone fracture in dialysis patients. However, ABD increases the risk of hypercalcemia because a decrease in calcium uptake by bone and might shorten the life span of dialysis patients.
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