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Published on: April 7, 2023
[Diabetes mellitus and the cerebrovascular disease]
Masahiro Maruyama1, Makoto Takizawa, Hitoshi Ishida
1The Third Department of Internal Medicine, Kyorin University School of Medicine.
Insights
Diabetes, a vascular disease, involves atherosclerosis and insulin resistance even in prediabetes. Understanding the link between diabetes, cerebrovascular issues, and calcium buildup is crucial for managing these conditions.
Area of Science:
- Cardiovascular Science
- Endocrinology
- Neurology
Context:
- Diabetes mellitus is recognized as a significant vascular disease.
- Atherosclerosis development, linked to insulin resistance, can begin in the prediabetic stage.
- Intravascular calcium precipitation is a notable feature in diabetes-related cerebrovascular disease.
Purpose:
- To elucidate the pathophysiological relationship between diabetes and cerebrovascular disease.
- To explore the connection between diabetes, atherosclerosis, and intravascular calcium precipitation.
- To review recent findings on the underlying links between diabetes and cerebrovascular disorders.
Summary:
- This review focuses on the intricate relationship between diabetes mellitus and cerebrovascular diseases.
- It highlights the early onset of atherosclerosis due to insulin resistance in prediabetes.
- The discussion emphasizes the role of intravascular calcium precipitation in this context.
Impact:
- Provides insights into the pathophysiology of diabetes-related vascular complications.
- Aims to improve understanding of cerebrovascular disease in diabetic patients.
- Contributes to the knowledge base for managing atherosclerotic disorders in diabetes.
Abstract:
Diabetes mellitus is, so called, the disease of the blood vessel. Indeed in many cases, atherosclerosis is already developed from the prediabetic state because of an existence of insulin resistance. Therefore, it is very important to elucidate the pathophysiological relationship between diabetes and cerebrovascular disease accompanied with intravascular calcium precipitation. Here we introduce the recent topics about the underlying relation between diabetes and cerebrovascular disease with atherosclerotic disorders.
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