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Updated: Aug 19, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
[Osteoporosis and vascular calcification]
Toru Yamaguchi1, Toshitsugu Sugimoto
1Division of Endocrinology/ Metabolism, Department of Internal Medicine, Takatsuki General Hosipital.
Abstract:
Many clinical studies have shown that osteoporosis is associated with atherosclerosis and cardiovascular death. Plasma lipids might be related to bone mass and bone fragility, and might be the common factor underlying both osteoporosis and atherosclerosis. It is interesting that statins, estrogens, and nitrogen-containing bisphosphonates have similar stimulatory effects on bone mass, because all of them are known to reduce LDL-cholesterol (C) and increase HDL-C in the plasma. Thus, these two disorders might be related to each other in terms of pathogenesis and therapeutic agents.
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