Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Bisphosphonate and markers for bone metabolism].

¹Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine.

Clinical Calcium

|March 19, 2005

Summary

Bisphosphonates (BPs) are crucial for treating bone diseases like osteoporosis. Choosing the right bone metabolism markers is essential for accurately assessing BP treatment effectiveness, especially for amino-containing BPs.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Association of low back pain and sleep quality with presenteeism.

Occupational medicine (Oxford, England)·2022

Same author

Histomorphometric Evaluation of Cartilage Degradation using Rabbit Articular Chondrocytes Cultured in Alginate Beads - Effects of Hyaluronan.

International journal of biomedical science : IJBS·2013

Same author

An open-label randomized controlled study of pegylated interferon/ribavirin combination therapy for chronic hepatitis C with versus without fluvastatin.

Journal of viral hepatitis·2012

Same author

Gender differences in maximum voluntary lip-closing force during lip pursing in healthy young adults.

Journal of oral rehabilitation·2011

Same author

Asymmetric lip-closing forces in children with repaired unilateral cleft lip and/or palate.

Journal of oral rehabilitation·2011

Same author

Regulatory relationship between tactile sensation at the vermilion of the lips and lip-closing force.

Journal of oral rehabilitation·2011

Area of Science:

Biochemistry
Pharmacology
Orthopedics

Context:

Bisphosphonates (BPs) are primary treatments for metabolic bone diseases, including osteoporosis and Paget's disease.
Guidelines for using bone metabolism markers in osteoporosis management have recently been established.
The efficacy of BPs in treating bone diseases is often monitored using bone metabolism markers.

Purpose:

To highlight the importance of selecting appropriate bone metabolism markers for evaluating bisphosphonate therapy.
To address the influence of bisphosphonate structure, specifically amino-containing side chains, on marker response.
To provide insights into the accurate prediction of treatment efficacy for metabolic bone diseases.

Summary:

Bisphosphonates are first-line treatments for osteoporosis and Paget's disease.
Bone metabolism markers are used to predict treatment efficacy, with recent guidelines proposed for osteoporosis.
The choice of bone metabolism markers significantly impacts the assessment of treatment changes, particularly for amino-containing bisphosphonates.

Impact:

Informing clinical decisions regarding the selection of bone metabolism markers for bisphosphonate therapy.
Improving the accuracy of treatment efficacy prediction in patients with metabolic bone diseases.
Guiding the development of more precise monitoring strategies for bisphosphonate treatment outcomes.

Related Experiment Videos