Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Vitamin K and bone metabolic marker].

M Shiraki1

  • 1Research Institute and Practice for Involutional Diseases.

Clinical Calcium
|March 19, 2005
PubMed
Summary

Vitamin K2 supplementation may improve bone health by increasing osteocalcin levels, a key marker for bone formation. This vitamin shows promise in managing osteoporosis beyond bone mineral content assessments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study of twice-weekly injections of Teriparatide by comparing efficacy with once-weekly injections in osteoporosis patients: the TWICE study.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2019
Same author

Multiple vitamin deficiencies additively increase the risk of incident fractures in Japanese postmenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Correction to: Stimulation of intestinal calcium absorption by orally administrated vitamin D3 compounds: a prospective open-label randomized trial in osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Modeling and simulation of bone mineral density in Japanese osteoporosis patients treated with zoledronic acid using tartrate-resistant acid phosphatase 5b, a bone resorption marker.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Stimulation of intestinal calcium absorption by orally administrated vitamin D3 compounds: a prospective open-label randomized trial in osteoporosis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2017
Same author

Restrictive pulmonary dysfunction is associated with vertebral fractures and bone loss in elderly postmenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2017

Area of Science:

  • Biochemistry
  • Endocrinology
  • Orthopedics

Context:

  • Osteoporosis management often relies on bone mineral content, which may not fully capture the effects of certain treatments.
  • Vitamin K has been linked to fracture prevention in osteoporosis.
  • The specific impact of Vitamin K2 on bone metabolism requires further investigation beyond traditional metrics.

Purpose:

  • To explore the efficacy of Vitamin K2 in improving bone health.
  • To identify reliable biomarkers for assessing Vitamin K2's effects on bone.
  • To investigate the relationship between Vitamin K2 administration and osteocalcin levels.

Summary:

  • Vitamin K2 treatment may positively influence bone health.
  • Bone mineral content is insufficient for evaluating Vitamin K2's bone effects.
  • Serum total osteocalcin and glu-osteocalcin are potential markers for Vitamin K2's impact.
  • Vitamin K2 administration altered these osteocalcin indices.
  • Vitamin K2 might enhance osteocalcin production or secretion by bone cells.

Impact:

  • Identifies serum osteocalcin as a potential biomarker for Vitamin K2 efficacy in osteoporosis.
  • Suggests a mechanism for Vitamin K2's bone-protective effects.
  • Provides a basis for further clinical trials on Vitamin K2 for bone health.

Related Experiment Videos