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A new tetracycline antibiotic with antitumor activity. II. The structural elucidation of SF2575
1Pharmaceutical Research Center, Meiji Seika Kaisha, Ltd., Yokohama, Japan.
The Journal of Antibiotics
|March 1, 1992
Abstract:
The structure of a new antitumor antibiotic SF2575, has been determined by spectroscopic analyses of the antibiotic and its alkaline degradation products. The relative stereochemistry has been confirmed by X-ray crystallographic analysis. The antibiotic has a 2-naphthacenecarboxamide carbon skelton which is structurally related to the tetracycline antibiotics and it is unique by bearing C-glycoside, salicyclic acid and angelic acid moieties.