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Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

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Related Experiment Video

Updated: Jul 13, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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[Epigastric pain and abnormal ECG].

Ch Laus1, M Danner, S Rüttimann

  • 1Abteilung Innere Medizin, Kantonsspital Schaffhausen.

Praxis
|March 23, 2005
PubMed
Summary

Acute pancreatitis can cause electrocardiogram (ECG) changes that mimic acute coronary syndrome. These ECG abnormalities resolved in a patient after pancreatitis treatment, highlighting the importance of considering pancreatitis in cardiac symptom differential diagnoses.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Internal Medicine

Background:

  • Acute coronary syndrome (ACS) is a common diagnosis for patients presenting with chest pain and ECG changes.
  • Cardiovascular risk factors include family history, smoking, hypercholesterinemia, and hypertension.
  • Acute pancreatitis is an inflammation of the pancreas, often presenting with abdominal pain.

Observation:

  • A 50-year-old male presented with upper abdominal pain and anterior T-wave inversions on ECG.
  • The patient had multiple cardiovascular risk factors.
  • Elevated amylase and lipase levels, along with abdominal ultrasound findings, confirmed acute pancreatitis.

Findings:

  • ECG abnormalities persisted during hospitalization but normalized three weeks post-discharge.

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  • Cardiologic evaluations were unremarkable.
  • The ECG changes were attributed to acute pancreatitis, not ACS.

    • Implications:

    • Acute pancreatitis can induce ECG changes that mimic ACS in up to 30% of cases.
    • Recognizing pancreatitis as a cause of ECG abnormalities is crucial for avoiding misdiagnosis and inappropriate treatment.
    • This case underscores the importance of a comprehensive differential diagnosis in patients with cardiac symptoms and abdominal pain.