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Related Experiment Videos

Hepatitis A vaccination--a prison-based solution for a community-based outbreak?

R L Gilbert1, T O'Connor, S Mathew

  • 1Prison Surveillance Unit, Communicable Disease Surveillance Centre, Health Protection Agency Centre for Infections, 61 Colindale Avenue, London NW9 5EQ. ruth.gilbert@hpa.org.uk

Communicable Disease and Public Health
|March 23, 2005
PubMed
Summary
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A hepatitis A outbreak in South Yorkshire was targeted by a prison vaccination campaign. This initiative successfully immunized many young male injecting drug users, suggesting prisons can be effective for community outbreak control.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • An increase in hepatitis A cases was observed in South Yorkshire starting December 2001, primarily affecting young males who inject drugs.
  • A community vaccination program initiated in November 2002 did not halt the ongoing outbreak.

Purpose of the Study:

  • To assess the impact of a prison-based vaccination campaign on a community hepatitis A outbreak.
  • To evaluate the effectiveness of utilizing correctional facilities for immunizing injecting drug users (IDUs).

Main Methods:

  • A four-week vaccination campaign was conducted in a local prison in March 2003.
  • 1,236 prisoners (91% of the inmate population) were vaccinated.
  • Demographic and risk factor data were collected, identifying 895 prisoners from the affected area, 52% of whom were injecting drug users.

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Main Results:

  • Hepatitis A notifications in South Yorkshire ceased in August 2003.
  • While the prison campaign may have been too late to impact the immediate outbreak, it successfully vaccinated a significant number of young male IDUs from the community.

Conclusions:

  • Prison-based vaccination interventions are a potentially effective strategy for immunizing the IDU population.
  • This approach can play a role in interrupting community-based infectious disease outbreaks, such as hepatitis A.