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Published on: January 29, 2018
Bone mass acquisition in healthy children
J H Davies1, B A J Evans, J W Gregory
1Department of Child Health, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. daviesjh@cf.ac.uk
Insights
Genetic factors significantly influence bone mass, but lifestyle choices in childhood are crucial for preventing osteoporosis later in life. Pediatricians can guide families toward healthy habits for optimal bone health.
Area of Science:
- Pediatrics
- Genetics
- Public Health
Background:
- Bone mass acquisition is influenced by multiple factors beyond genetics.
- Childhood is a critical period for establishing peak bone mass.
- Osteoporosis risk is linked to bone mass accumulated during early life.
Purpose of the Study:
- To review genetic, fetal, and environmental factors affecting bone mass in children.
- To identify pediatrician roles in promoting childhood bone health.
- To emphasize lifestyle modifications for preventing osteoporosis.
Main Methods:
- Literature review of studies on bone mass determinants in children.
- Analysis of genetic, fetal, and environmental influences.
- Identification of actionable recommendations for pediatricians.
Main Results:
- Genetics accounts for 80% of bone mass variance.
- Fetal and environmental factors significantly impact bone accumulation.
- Lifestyle choices are modifiable determinants of future bone health.
Conclusions:
- Pediatricians play a key role in counseling families on bone-healthy lifestyles.
- Early life interventions can mitigate osteoporosis risk.
- A comprehensive approach considering all influences is vital for pediatric bone health.
Abstract:
Although 80% of the variance in bone mass is determined genetically, there are many other factors which influence the accumulation of bone in early life and affect future risks of osteoporosis. This review considers the genetic, fetal, and environmental influences on bone mass acquisition in healthy children, and highlights important areas where paediatricians may have a role by counselling children and their families to adopt a healthy lifestyle which promotes bone health.
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