Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vanishing CT lesions in epilepsy.

J S Chopra1, I M Sawhney, N Suresh

  • 1Department of Neurology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

Journal of the Neurological Sciences
|January 1, 1992
PubMed
Summary

Computed tomography (CT) scans revealed specific cerebral lesions in epilepsy patients that resolved spontaneously with anticonvulsant therapy. Further research is needed to understand the exact nature of these transient brain lesions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness of an oral health education intervention among 6-12-year-old children: A cluster randomized controlled trial.

Community dental health·2023
Same author

Human papillomavirus related oropharyngeal cancer: identifying and quantifying topics of patient interest.

The Journal of laryngology and otology·2023
Same author

Benign Recurrent Intrahepatic Cholestasis - Unravelleing the Paradox.

Indian pediatrics·2021
Same author

Discovery and Validation of a Three-Cytokine Plasma Signature as a Biomarker for Diagnosis of Pediatric Tuberculosis.

Frontiers in immunology·2021
Same author

Dual Internal Pancreatic Fistulae Complicating Chronic Pancreatitis.

Indian journal of pediatrics·2020
Same author

Effect of preoperative oral administration of steroids in comparison to an anti-inflammatory drug on postoperative pain following single-visit root canal treatment - a double-blind, randomized clinical trial.

International endodontic journal·2020

Area of Science:

  • Neurology
  • Radiology
  • Epileptology

Background:

  • Computed tomography (CT) in epilepsy patients has highlighted prevalent cerebral lesions.
  • The spontaneous resolution of these lesions with anticonvulsant therapy suggests a unique pathological process.
  • The precise nature and etiology of these transient cerebral lesions remain unclear.

Observation:

  • A study of 122 epilepsy patients (77 male, 45 female) aged 3-57 years with various seizure types.
  • Electroencephalogram (EEG) was abnormal in 84% of 100 patients, with 40 showing CT-correlated localization.
  • Plain CT revealed low attenuation lesions at the cortical-subcortical junction in all patients.

Findings:

  • Contrast-enhanced CT showed various lesion morphologies including ring (40.9%), disc (38.5%), and target (2.5%) lesions.

Related Experiment Videos

  • Follow-up scans in 78 patients demonstrated complete lesion disappearance in 60.3% within 6-12 weeks.
  • Partial or complete resolution was observed in the remaining patients, with some showing residual specks.

    • Implications:

    • These findings underscore the transient nature of specific cerebral lesions in epilepsy patients.
    • The study highlights the importance of follow-up imaging to assess lesion resolution.
    • Understanding these lesions may offer new insights into epilepsy pathophysiology and treatment.