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Published on: August 4, 2022
ANCA-associated renal vasculitis--epidemiology, diagnostics and treatment
1Nephrology Department of the First Faculty of Medicine, Charles University in Prague, Czech Republic. zrihova@seznam.cz
Abstract:
The pauciimmune small-vessel vasculitides are multisystem diseases with frequent renal involvement. They are strongly associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA). In this review we have focused on the ethiopathogenesis and the role of ANCA, clinical presentation and histopathologic findings of different ANCA - associated vasculitides (AAV). Current treatment strategies and the overall and renal outcome of patients with AAV are also discussed.
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