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Experimental therapeutic intervention with ascorbic acid in ethanol induced testicular injuries in rats
M Maneesh1, H Jayalakshmi, Sanjiba Dutta
1Department of Biochemistry, Sikkim Manipal Institute of Medicine Sciences, Gangtok, India.
Indian Journal of Experimental Biology
|March 24, 2005
Abstract:
Ascorbic acid treatment significantly increased the activities of testicular delta5, 3beta-HSD and 17beta-HSD. Moreover, the treatment was also associated with significant decrease in oxidative stress in the testis. Ethanol induced oxidative stress and decreased steroidogenesis can be reversed by treatment with ascorbic acid.
