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A Non-Coding Small RNA MicC Contributes to Virulence in Outer Membrane Proteins in Salmonella Enteritidis
Published on: January 27, 2021
Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice
Ferric C Fang1, Stephen J Libby, Margaret E Castor
1Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-7242, USA. fcfang@u.washington.edu
Infection and Immunity
|March 24, 2005
Abstract:
Isocitrate lyase is required for fatty acid utilization via the glyoxylate shunt. Although isocitrate lyase is essential for Salmonella persistence during chronic infection, it is dispensable for acute lethal infection in mice. Substrate availability in the phagosome appears to evolve over time, with increasing fatty acid dependence during chronic infection.

