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Everyday memory impairment of patients with mild cognitive impairment

Hiroaki Kazui1, Akemi Matsuda, Nobutsugu Hirono

  • 1Psychiatry and Behavioral Science, Osaka University Graduate School of Medicine, Osaka, Japan. kazui@psy.med.osaka-u.ac.jp

Dementia and Geriatric Cognitive Disorders
|March 24, 2005
PubMed

Insights

Mild cognitive impairment (MCI) patients show everyday memory deficits, milder than Alzheimer

Area of Science:

  • Neuroscience
  • Gerontology
  • Psychology

Background:

  • Mild cognitive impairment (MCI) represents a transitional stage between normal aging and Alzheimer's disease (AD).
  • Accurate diagnosis of MCI is crucial for timely intervention and management.
  • Everyday memory function is a key indicator of cognitive health and daily functioning.

Purpose of the Study:

  • To evaluate everyday memory impairment in patients with mild cognitive impairment (MCI).
  • To compare the performance of MCI patients on the Rivermead Behavioral Memory Test (RBMT) with normal controls (NC) and Alzheimer's disease (AD) patients.
  • To assess the diagnostic utility of the RBMT in identifying MCI.

Main Methods:

  • The Rivermead Behavioral Memory Test (RBMT) was administered to 24 MCI patients, 48 normal controls (NC), and 48 Alzheimer's disease (AD) patients.
  • Participants were matched for age, sex, and education.
  • Performance on various memory tasks, including delayed recall and route retracing, was analyzed.

Main Results:

  • MCI patients exhibited overall everyday memory impairment, less severe than that observed in AD patients.
  • MCI patients struggled with delayed recall tasks and recalling/retracing a simple new route.
  • Immediate recall performance was generally preserved in MCI patients.
  • The RBMT total Profile score achieved 100% accuracy in classifying MCI patients and 91.7% in classifying NC.
  • Prospective memory tasks did not effectively differentiate MCI patients from controls.

Conclusions:

  • The Rivermead Behavioral Memory Test (RBMT) is a valuable tool for diagnosing mild cognitive impairment (MCI).
  • MCI is characterized by specific deficits in delayed recall and spatial memory tasks.
  • The RBMT's Profile score demonstrates high diagnostic accuracy for MCI, distinguishing it from normal cognition.

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