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Burns and smoke inhalation.

T L Lee-Chiong1, R A Matthay

  • 1Pulmonary and Critical Care Section, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

Current Opinion in Pulmonary Medicine
|March 1, 1995
PubMed
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Smoke inhalation injury is common in burn victims, especially those trapped in fires. Firesmoke contains toxic gases like carbon monoxide and hydrogen cyanide, causing lung and systemic damage.

Area of Science:

  • Emergency Medicine
  • Toxicology
  • Pulmonary Medicine

Background:

  • Smoke inhalation injury is a significant concern, affecting up to one-third of major burn victims.
  • Exposure is likely in individuals trapped in confined spaces or losing consciousness during fires.
  • Firesmoke composition varies based on burning materials, temperature, and oxygen availability.

Purpose of the Study:

  • To highlight the diverse toxicities of firesmoke constituents.
  • To emphasize the importance of suspecting smoke inhalation in fire-related injuries.
  • To underscore the need for considering all smoke components in victim assessment.

Main Methods:

  • Review of existing literature on smoke inhalation injury.
  • Analysis of firesmoke composition and its toxicological effects.

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  • Clinical considerations for diagnosing and managing smoke inhalation.
  • Main Results:

    • Firesmoke contains thermal loads and toxic gases (CO, HCN, NOx).
    • Each smoke constituent can cause pulmonary and systemic toxicity.
    • Variable smoke composition necessitates a thorough evaluation of each victim.

    Conclusions:

    • Suspect smoke inhalation in all fire-related injuries, particularly in confined spaces or with loss of consciousness.
    • Recognize the potential for diverse toxicities from various firesmoke components.
    • Comprehensive assessment considering all inhaled substances is crucial for effective patient management.