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Bioactive asterosaponins from the starfish Culcita novaeguineae
Hai-Feng Tang1, Yang-Hua Yi, Ling Li
1Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, People's Republic of China. tanghaifeng71@126.com
Abstract:
Two new sulfated steroidal pentaglycosides (asterosaponins), novaeguinosides I (2) and II (3), along with the known regularoside B (1) were isolated from the starfish Culcita novaeguineae. Their structures were elucidated by extensive NMR techniques as well as chemical evidence. The new asterosaponins showed marginal in vitro cytotoxicity against two human tumor cell lines.
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