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Published on: May 27, 2010
Arrhythmogenic right ventricular cardiomyopathy in two cats
A M Harvey1, I A Battersby, M Faena
1University of Bristol, Department of Clinical Veterinary Science, Division of Companion Animals, Langford House, Langford, Bristol.
Insights
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare cardiac disease in animals, characterized by fibro-fatty tissue infiltration. This study details ARVC in two cats presenting with heart failure and arrhythmias, highlighting its potential severity.
Area of Science:
- Veterinary Cardiology
- Pathology
- Animal Health
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary myocardial disease.
- It is characterized by fibro-fatty infiltration of the myocardium.
- ARVC is a significant cause of sudden cardiac death in humans, but is rarely reported in animals.
Observation:
- This report details two feline cases of ARVC.
- Cats presented with clinical signs of right-sided congestive heart failure and syncope.
- Electrocardiography revealed complete atrioventricular block and ventricular ectopics, including ventricular tachycardia.
Findings:
- Echocardiography showed marked right ventricular and atrial dilation with hypokinesis.
- Histopathology confirmed fibro-fatty infiltration of the myocardium, primarily in the right ventricular free wall.
- Survival times post-diagnosis were short, averaging 9.5 days.
Implications:
- This study expands the understanding of ARVC in veterinary medicine.
- It highlights the importance of considering ARVC in cats with heart failure and arrhythmias.
- Further research into ARVC in feline populations is warranted.
Abstract:
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a disease characterised by infiltration of the myocardium by adipose and fibrous tissue. The disease is an important cause of sudden death in humans, but has rarely been described in animals. This report describes ARVC in two cats with right-sided congestive heart failure. One cat had also experienced previous episodes of syncope. Standard six-lead and 24-hour (Holter) electrocardiogram recording revealed complete atrioventricular block and multiform ventricular ectopics in both cats, with the addition of ventricular tachycardia, ventricular bigeminy and R-on-T phenomenon in one of them. On echocardiography, the right ventricle and atrium were massively dilated and hypokinetic. The survival times of the cats were three days and 16 days following diagnosis. Histopathology in one case revealed fibro-fatty infiltration of the myocardium, predominantly affecting the right ventricular free wall.
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