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[Hematuria and proteinuria in childhood]
P Parvex1, F Cachat, E Girardin
1Unité romande de néphrologie, pédiatrique, Département de pédiatrie, Hôpital des Enfants, 1211 Genève 14.
Insights
Early investigation of childhood hematuria (blood in urine) and proteinuria (protein in urine) is crucial for identifying severe kidney diseases like glomerulonephritis and avoiding unnecessary tests for benign conditions.
Area of Science:
- Pediatric Nephrology
- Clinical Investigation
- Diagnostic Medicine
Context:
- Hematuria and proteinuria are common findings in pediatric primary care.
- Prompt evaluation is necessary to differentiate serious kidney conditions from benign ones.
- Distinguishing between glomerular and urologic causes is essential.
Purpose:
- To outline an effective diagnostic approach for children presenting with proteinuria and/or hematuria.
- To emphasize the importance of early identification of severe kidney diseases.
- To guide primary care physicians in managing these common pediatric findings.
Summary:
- Proteinuria and hematuria in children can signal severe kidney diseases, including glomerulonephritis.
- Primary care evaluation should initiate investigations to rapidly identify serious conditions.
- Benign conditions like orthostatic proteinuria require avoiding excessive testing, while urologic causes must be ruled out for isolated hematuria.
Impact:
- Facilitates timely diagnosis and management of pediatric kidney diseases.
- Reduces healthcare costs by preventing unnecessary investigations.
- Improves patient outcomes through early detection of serious pathologies.
Abstract:
Hematuria and proteinuria are often the first signs of potentially severe kidney diseases. Investigations of a child with proteinuria +/- hematuria should start at the primary care physician office, and will permit to rapidly identify the most serious kidney diseases, such as the glomerulonephritis, but also to avoid excessive and costly investigations in patients with a benign condition such as orthostatic proteinuria. Isolated microscopic hematuria is also relatively frequently found during routine pediatric office visit. Secondary to a glomerulonephritis, it is often associated with proteinuria. Urologic causes should be excluded in case of isolated microscopic or macroscopic hematuria.
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