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Updated: Jul 28, 2026

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Published on: June 9, 2023
Gastric carcinoma and thyroid status
E G Kandemir1, A Yonem, Y Narin
1Medical Oncology Department, GATA Haydarpasa Training Hospital, Kadikoy, Istanbul, Turkey. egkandemir@yahoo.com
Gastric cancer patients show a higher frequency of thyroid disorders, including goitre and autoimmune thyroid disease, compared to healthy individuals. This suggests a significant link between gastric cancer and thyroid health.
Area of Science:
- Endocrinology
- Gastroenterology
- Oncology
Background:
- Dietary iodine levels (deficiency or excess) are linked to gastric carcinoma prevalence.
- Thyroid diseases share risk factors with gastric carcinoma, suggesting a potential connection.
Purpose of the Study:
- To investigate the frequency of thyroid disorders in patients with gastric carcinoma.
- To compare thyroid health in gastric cancer patients versus healthy controls.
Main Methods:
- Physical examination of thyroid health.
- Measurement of serum thyroid hormones.
- Assay of thyroid autoantibodies in 61 gastric carcinoma patients and 55 controls.
Main Results:
- Goitre was more prevalent in gastric cancer patients (49.1%) than controls (20%).
- Non-toxic goitre and autoimmune thyroid disease were significantly more frequent in gastric cancer patients.
- 27.8% of gastric cancer patients had autoimmune thyroid disease vs. 10.9% of controls.
Conclusions:
- A significant association exists between gastric cancer and thyroid disorders.
- Thyroid health evaluation may be relevant in gastric cancer patients.
- Further research into the mechanisms linking gastric cancer and thyroid disease is warranted.
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