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Common variable immunodeficiency in a family
D J Van Spronsen1, M Kerbert-Dreteler, G van der Sluijs Veer
1Department of Internal Medicine, Oncology/AIDS division, Medisch Spectrum Twente/Ziekenhuis Enschede, Netherlands.
The Netherlands Journal of Medicine
|February 1, 1992
Abstract:
Common variable immunodeficiency (CVID) is mainly characterised by hypo- or agammaglobulinaemia of late onset, usually discovered in the second decade of life. In individuals CVID is associated with a variable impairment of cellular immunity and the susceptibility to microbial infection may vary as well. CVID is described in a mother and a son who suffered from serious bacterial infections. In addition, minor immunological test abnormalities of apparently healthy first degree relatives are described.