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Related Experiment Videos

Gene tree distributions under the coalescent process.

James H Degnan1, Laura A Salter

  • 1Department of Mathematics and Statistics, University of New Mexico, Albuquerque, New Mexico 87131, USA. james@stat.unm.edu

Evolution; International Journal of Organic Evolution
|March 29, 2005
PubMed
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Lineage sorting causes gene tree variability. This study presents a method to compute gene tree distributions under the coalescent model, aiding in species tree inference and analysis.

Area of Science:

  • Population genetics
  • Computational evolutionary biology
  • Phylogenetics

Background:

  • The coalescent model explains genetic variation within species.
  • Lineage sorting introduces variability between gene trees and species trees.
  • Understanding gene tree distributions is crucial for accurate phylogenetic inference.

Purpose of the Study:

  • To develop a method for calculating gene tree topology distributions.
  • To analyze the impact of species tree parameters on gene tree distributions.
  • To provide a computational tool for these analyses.

Main Methods:

  • Derivation of a method to compute gene tree distributions under the coalescent model.
  • Application to bifurcating species trees with an arbitrary number of taxa.

Related Experiment Videos

  • Examination of gene tree distribution shapes and sensitivities.

    • Main Results:

    • A method for computing gene tree distributions is derived.
    • The method allows for exact probability calculations of topological equivalence.
    • Gene tree distribution shapes are analyzed for sensitivity to various parameters.

    Conclusions:

    • The derived method provides a robust framework for analyzing gene tree distributions.
    • This work facilitates more accurate species tree inference and phylogenetic analysis.
    • The COAL program implements this method for practical application.