Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessing cortical functional connectivity by linear inverse estimation and directed transfer function: simulations

L Astolfi1, F Cincotti, D Mattia

  • 1IRCCS Fondazione Santa Lucia, Rome, Italy. laura.astolfi@.uniroma1.it

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
|March 29, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic submucosal dissection versus endoscopic mucosal resection for colorectal laterally spreading tumors (> 20 mm): a systematic review and meta-analysis.

Techniques in coloproctology·2026
Same author

Nivolumab plus ipilimumab and cobimetinib in previously treated microsatellite-stable/DNA mismatch repair-proficient metastatic colorectal cancer: the phase II CheckMate 142 trial.

ESMO gastrointestinal oncology·2026
Same author

Nomogram based on the pre-treatment systemic oxidative stress score to predict the prognosis of surgically treated patients with oral squamous cell carcinoma: competing risk model analysis.

International journal of oral and maxillofacial surgery·2026
Same author

[Changes in murine skin odors following <i>Plasmodium</i> infections and their impact on mosquito attraction].

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control·2025
Same author

MFSnet: a multi-scale feature screening network for chicken counting in dense environments.

British poultry science·2025
Same author

[Epidemiological characteristics and influencing factors of diabetes and pre-diabetes among adult residents in Hainan Province].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2025

Directed Transfer Function (DTF) effectively estimates human cortical connectivity using high-resolution EEG. This advanced technique works reliably under practical recording conditions, offering a powerful alternative to fMRI.

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Biomedical Engineering

Background:

  • Estimating human cortical connectivity is crucial for understanding brain function.
  • Traditional methods face challenges due to signal spread from the cortex to sensors.
  • High-resolution electroencephalography (EEG) offers improved spatial resolution for brain activity mapping.

Purpose of the Study:

  • To evaluate the Directed Transfer Function (DTF) method for estimating cortical connectivity.
  • To validate DTF using both simulated data and real-world high-resolution EEG recordings.
  • To assess the performance of DTF under varying signal-to-noise ratios (SNR) and data lengths.

Main Methods:

  • Utilized Directed Transfer Function (DTF), a frequency-domain approach based on multivariate autoregressive modeling and Granger causality.

Related Experiment Videos

  • Applied DTF to cortical signals estimated from high-resolution EEG recordings.
  • Conducted simulation studies with controlled SNR and temporal length, followed by ANOVA.
  • Analyzed high-resolution EEG data from a visually paced finger movement task.

    • Main Results:

    • DTF accurately estimated simulated connectivity patterns under specific conditions.
    • Optimal performance required a Signal to Noise Ratio (SNR) of at least 3 and 75 seconds of data (at 64 Hz sampling rate).
    • These conditions are generally met in practical EEG recordings.

    Conclusions:

    • High-resolution EEG combined with linear inverse estimation and DTF effectively estimates functional cortical connectivity.
    • This EEG-based approach provides a viable alternative to functional MRI (fMRI) for cortical connectivity estimation.
    • Advanced computational techniques applied to modern EEG recordings enable robust brain connectivity analysis.