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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

[Moderate cognitive impairment syndrome in cerebral vascular insufficiency]

N N Iakhno, V V Zakharov, A B Lokshina

    Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
    |March 29, 2005
    PubMed

    Insights

    Mild cognitive impairment (MCI) affects two-thirds of patients with cerebral vascular insufficiency (CVI). Cognitive hypoactivity and memory deficits are key indicators, suggesting potential neurodegeneration in these patients.

    Area of Science:

    • Neurology
    • Psychiatry
    • Neuropsychology

    Background:

    • Cerebral vascular insufficiency (CVI) is a common condition affecting older adults.
    • Mild cognitive impairment (MCI) is a frequent complication of CVI, impacting daily functioning.
    • Understanding the specific clinical and psychological features of MCI in CVI is crucial for diagnosis and management.

    Purpose of the Study:

    • To investigate the frequency and characteristics of mild cognitive impairment (MCI) in patients with cerebral vascular insufficiency (CVI).
    • To identify distinct clinical and psychological patterns of cognitive deficits in this patient group.

    Main Methods:

    • A cohort of 42 patients with CVI underwent neurological examinations.
    • Psychiatric and neuropsychological scales and tests were administered to assess cognitive function.
    • Patients were evaluated for the presence and type of mild cognitive impairment (MCI).

    Main Results:

    • Mild cognitive impairment (MCI) was diagnosed in 66.7% of the studied patients.
    • Cognitive hypoactivity, affecting neurodynamics and voluntary activity regulation, was observed in 47.6% of patients, potentially indicating subcortical and frontal lobe involvement.
    • Memory impairment, characteristic of hippocampus lesions, was noted in 20.1% of patients.

    Conclusions:

    • Mild cognitive impairment (MCI) is highly prevalent in patients with cerebral vascular insufficiency (CVI).
    • Specific patterns of cognitive deficits, including hypoactivity and memory impairment, are identifiable.
    • The findings suggest a potential for concomitant neurodegeneration in patients presenting with amnesic MCI within the CVI context.

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