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RNA and protein folding: common themes and variations

D Thirumalai1, Changbong Hyeon

  • 1Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, USA. thirum@glue.umd.edu

Biochemistry
|March 30, 2005
PubMed
Summary

This study unifies RNA and protein folding using polymer theory, revealing that RNA folding barriers scale similarly to proteins. It introduces the kinetic partitioning mechanism (KPM) to explain folding pathways and chaperone roles.

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