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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Multiple risk assessment of cardiovascular surgery in chronic renal failure patients

Bartlomiej Witczak1, Anders Hartmann, Jan L Svennevig

  • 1Department of Medicine, Section of Nephrology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway. bartlomiej.witczak@rikshospitalet.no

The Annals of Thoracic Surgery
|March 31, 2005
PubMed

Insights

Cardiovascular surgery in patients with chronic renal failure leads to increased complications and significantly higher short-term and long-term mortality. Key risk factors include age, COPD, diabetes, and dialysis dependence.

Area of Science:

  • Cardiovascular Surgery
  • Nephrology
  • Critical Care Medicine

Background:

  • Chronic renal failure (CRF) is a significant risk factor for adverse outcomes in cardiovascular surgery.
  • This study evaluates the results of cardiovascular surgery in patients with CRF compared to a matched control group.

Purpose of the Study:

  • To assess the outcomes of cardiovascular surgery in patients with chronic renal failure.
  • To identify preoperative risk factors associated with mortality in this patient population.

Main Methods:

  • A retrospective analysis of 106 patients with CRF undergoing cardiovascular surgery between 1990 and 2000.
  • Patients were matched with 106 controls based on age, sex, year of operation, type of operation, and diabetes status.

Main Results:

  • CRF patients experienced longer ventilation support, ICU, and hospital stays.
  • CRF patients required more blood product transfusions.
  • Early mortality (16% vs 6.6%) and 5-year mortality (79% vs 39%) were substantially higher in the CRF group.

Conclusions:

  • Patients with chronic renal failure undergoing cardiovascular surgery face increased postoperative complications and significantly higher mortality rates.
  • Independent preoperative risk factors for mortality in CRF patients include advanced age, chronic obstructive pulmonary disease, diabetes, and dialysis dependence.
Abstract

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