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Aortic valve prolapse associated with outlet-type ventricular septal defect
Shuenn-Nan Chiu1, Jou-Kou Wang, Ming-Tai Lin
1Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
The Annals of Thoracic Surgery
|March 31, 2005
Summary
Aortic valve prolapse is common in outlet ventricular septal defects, with similar onset ages across types. Larger shunts may predict earlier prolapse, highlighting the importance of defect location.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Aortic valve prolapse is frequently linked to juxta-arterial ventricular septal defects (VSDs).
- The association between aortic valve prolapse and other VSD outlet types is not well understood.
Purpose of the Study:
- To investigate the significance of aortic valve prolapse in various types of outlet ventricular septal defects.
- To determine factors influencing the onset and presentation of aortic valve prolapse in VSD patients.
Main Methods:
- Retrospective review of 677 patients undergoing surgical repair for outlet VSDs from 1987 to 2002.
- Classification of VSDs into juxta-arterial, perimembranous outlet, and muscular outlet types based on surgical findings.
Main Results:
- Aortic valve prolapse occurred in 57.2% of patients, with varying frequencies across VSD types.
- Significant aortic regurgitation developed in 14% of those with prolapse.
- Onset age of prolapse was similar across VSD types (around 5 years); larger shunts and anterior malalignment predicted earlier onset.
Conclusions:
- The location of outlet VSDs correlates with associated conditions like anterior septal malalignment, infundibular stenosis, and subaortic ridge.
- Aortic valve prolapse onset is similar across VSD types, but larger shunts may lead to earlier presentation.