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A Freeze-Thawing Method to Prepare Chitosan-Poly(vinyl alcohol) Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
Published on: January 14, 2020
Study on the synergetic degradation of chitosan with ultraviolet light and hydrogen peroxide
Shi-Ming Wang1, Qun-Zeng Huang, Qiong-Sheng Wang
1College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, China. fjwsm@tom.com
Abstract:
Chitosan was effectively degraded by hydrogen peroxide under irradiation with ultraviolet light. The existence of a synergetic effect on the degradation was demonstrated by means of viscometry. In addition, the optimal conditions of degradation were determined on the basis of orthogonal tests. The structure of the degraded product was characterized by Fourier-transform infrared spectra (FTIR) analysis and diffuse reflectance spectra (DRS) analysis. The mechanism of the degradation of chitosan was correlated with cleavage of the glycosidic bond.

