Related Experiment Video

Updated: Aug 17, 2026

In vitro Cell Migration and Invasion Assays
09:55

In vitro Cell Migration and Invasion Assays

Published on: June 1, 2014

Scratch n' screen for inhibitors of cell migration

Jon Soderholm1, Rebecca Heald

  • 1Molecular and Cell Biology Department, University of California, Berkeley 94720, USA.

Chemistry & Biology
|March 31, 2005
PubMed

Abstract:

Yarrow et al. have identified a small molecule inhibitor of cell migration, 3-(4-pyridyl)indole ("Rockout"), that targets Rho-kinase via a novel screening method using a scratch wound healing assay adapted to a high-throughput format and automated microscopy.

More Related Videos

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay
11:20

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay

Published on: November 17, 2017

Optimized Scratch Assay for In Vitro Testing of Cell Migration with an Automated Optical Camera
05:27

Optimized Scratch Assay for In Vitro Testing of Cell Migration with an Automated Optical Camera

Published on: August 8, 2018

Related Experiment Videos

Last Updated: Aug 17, 2026

In vitro Cell Migration and Invasion Assays
09:55

In vitro Cell Migration and Invasion Assays

Published on: June 1, 2014

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay
11:20

Evaluation of the Cell Invasion and Migration Process: A Comparison of the Video Microscope-based Scratch Wound Assay and the Boyden Chamber Assay

Published on: November 17, 2017

Optimized Scratch Assay for In Vitro Testing of Cell Migration with an Automated Optical Camera
05:27

Optimized Scratch Assay for In Vitro Testing of Cell Migration with an Automated Optical Camera

Published on: August 8, 2018

Related Concept Videos

Cell Migration01:09

Cell Migration

Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.

Articles linked to this work by shared authors, journal, and citation graph.

Beyond Kleiber's Law: Variation and Mechanisms of Metabolic Scaling.

Annual review of cell and developmental biology·2026

Building life from a bigger blueprint: Embryogenesis in whole-organism tetraploids.

Cell reports·2026

Ploidy and neuron size impact nervous system development and function in Xenopus.

Cell reports·2026

A modular tissue-clearing framework integrated with light-field microscopy enables rapid volumetric phenotyping of cardiac tissue.

Research square·2026

The nuclear-cytoplasmic ratio controls the cell-cycle period in compartmentalized frog egg extract.

Current biology : CB·2025

Fixation and Expansion Microscopy of Xenopus Egg Extract Spindles.

Bio-protocol·2025

DIVERSE System: De Novo Creation of Peptide Tags for Non-enzymatic Covalent Labeling by In Vitro Evolution for Protein Imaging Inside Living Cells.

Chemistry & biology·2015

Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis.

Chemistry & biology·2015

Synthetic Peptides as cGMP-Independent Activators of cGMP-Dependent Protein Kinase Iα.

Chemistry & biology·2015

Unraveling the B. pseudomallei Heptokinase WcbL: From Structure to Drug Discovery.

Chemistry & biology·2015

Vitamin C as Cancer Destroyer, Investigating Sulfhydration, and the Variability in CFTR Interactome.

Chemistry & biology·2015

Human ISPD Is a Cytidyltransferase Required for Dystroglycan O-Mannosylation.

Chemistry & biology·2015

Development of Phenoxyacetic Acid Hybrids With COX-2 Inhibitory Activity as Potential Anti-Neuroinflammatory Agents.

Drug development research·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us