Related Experiment Video
Updated: Aug 11, 2026

Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity
Published on: October 28, 2013
A low-cost, portable generic biotoxicity assay for environmental monitoring applications
Vivek Sharma1, Arthi Narayanan, Thirumalai Rengachari
1Department of Electrical Engineering and Computer Science, 220A Owen Hall, Oregon State University, Corvallis, 97331 OR, USA. sharmavi@ece.orst.edu
Abstract:
Fish chromatophores have been shown to be promising biosensors for the detection of hostile agents in the environment. However, state-of-art methods for such applications are still based on extensive use of data/signal processing, in conjunction with need for a skilled human observer to carry out the detection. As a result, conventional methods are complex, costly and cumbersome rendering them useless for field applications requiring low-cost portable solutions capable of fast detection. A new technique is proposed based on the popular scheme of observing the aggregation response in chromatophores for detection of toxicity, and a solution using optical detection and electronic processing is outlined. This scheme has the advantage of being low in cost while providing simple, fast and reliable detection.
More Related Videos
Related Concept Videos
Microbial Biosensors
Automated Microbial Diagnostics

