Related Experiment Video
Updated: Aug 14, 2026

Giant Liposome Preparation for Imaging and Patch-Clamp Electrophysiology
Published on: June 21, 2013
Wetting fibers with liposomes
N Borghi1, K Alias, P-G de Gennes
1Laboratoire PCC Institut Curie/CNRS UMR 168, 11, rue P. & M. Curie, 75005 Paris, France.
Abstract:
Giant unilamellar vesicles (GUVs) are deposited on glass microfibers. The vesicles adopt the classical "onduloidal" shape of liquid droplets on fibers. They spread by two simultaneous mechanisms: envelopment and emission of a precursor film. This film spreads faster than on a uniform plane surface and eventually stops, signaling the presence of defects on the rod. This fast spreading tenses the vesicles; transient pores open on the GUVs and the internal liquid leaks out. This process leads to a new technique for fiber coating.

