Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone ingrowth simulation for a concept glenoid component design.

A Andreykiv1, P J Prendergast, F van Keulen

  • 1Faculty of Design, Engineering and Production, Delft University of Technology, Mekelweg 2, 2628 CD Delft, The Netherlands. a.andreykiv@wbmt.tudelft.nl

Journal of Biomechanics
|March 31, 2005
PubMed
Summary

Primary fixation is key for uncemented total shoulder arthroplasty bone ingrowth. Proper fixation reduces micromotions, promoting healing and preventing fibrous tissue formation for better glenoid component stability.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Graded or random - Effect of pore distribution in 3D titanium scaffolds on corrosion performance and response of hMSCs.

Biomaterials advances·2024
Same author

Design of a calorimeter for near-field heat transfer measurements and thermal scanning probe microscopy.

The Review of scientific instruments·2021
Same author

Irradiation with 365 nm and 405 nm wavelength shows differences in DNA damage of swine pancreatic islets.

PloS one·2020
Same author

The combined antibacterial and anticancer properties of nano Ce-containing Mg-phosphate ceramic.

Life sciences·2020
Same author

Engineering biological gradients.

Journal of applied biomaterials & functional materials·2019
Same author

Computer aided design of architecture of degradable tissue engineering scaffolds.

Computer methods in biomechanics and biomedical engineering·2017

Area of Science:

  • Orthopedic surgery
  • Biomaterials engineering
  • Computational biomechanics

Background:

  • Glenoid component loosening is a primary complication in total shoulder arthroplasty.
  • Uncemented glenoid components with porous tantalum backing offer a potential solution for improved fixation.
  • Achieving direct post-operative stability is crucial for successful bone ingrowth into porous implants.

Purpose of the Study:

  • To investigate the feasibility of bone ingrowth in uncemented glenoid components.
  • To analyze the influence of primary fixation, elastic properties, and interface friction on bone ingrowth.
  • To model the relationship between micromotions, cellular response, and implant stability.

Main Methods:

  • Development of finite element models for three glenoid components with varying primary fixation.

Related Experiment Videos

  • Simulation of bone ingrowth based on interface micromotions and mesenchymal stem cell mechanoregulation.
  • Analysis of load distribution and its effect on interface micromotions.

    • Main Results:

    • Primary fixation significantly impacts bone ingrowth by optimizing load distribution and reducing peak interface micromotions.
    • Friction plays a secondary role in bone ingrowth when adequate primary fixation is present.
    • Less stiff backing materials can inhibit bone ingrowth due to increased micromotions and fibrous tissue formation.

    Conclusions:

    • Effective primary fixation is essential for promoting bone ingrowth in porous tantalum glenoid components.
    • The mechanical properties of the implant and interface friction are critical factors influencing long-term component stability.
    • Understanding these factors can guide the design of improved uncemented glenoid components for total shoulder arthroplasty.