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[Honey-induced poisoning].

S Geroulanos1, B Attinger, M Cakmakçi

  • 1Departement Chirurgie, Universitätsspital Zürich.

Schweizerische Rundschau Fur Medizin Praxis = Revue Suisse De Medecine Praxis
|April 21, 1992
PubMed
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Honey intoxications, caused by grayanotoxins from rhododendron nectar, are reappearing due to natural product preference. Symptoms like loss of consciousness and vomiting are acute but typically resolve within 24 hours.

Area of Science:

  • Toxicology
  • Botany
  • Pharmacology

Background:

  • Increasing consumer preference for natural products, including honey, is leading to a resurgence of intoxications.
  • Honey adulteration or contamination with toxic floral sources poses a public health concern.

Observation:

  • Approximately 8 cases of honey-induced intoxication are reported annually at the hospital in Trabzon.
  • Observed clinical presentations mirror historical accounts dating back 2400 years.

Findings:

  • Intoxications are primarily caused by grayanotoxins, diterpenes found in various rhododendron species.
  • Key symptoms include acute onset of loss of consciousness, weakness, excessive salivation, sweating, vomiting, and diarrhea.
  • Additional symptoms may involve circumoral paresthesias and bradyarrhythmia; fatalities are exceedingly rare.

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Implications:

  • This highlights the need for vigilance regarding honey sourcing, especially from direct beekeeper sales.
  • Symptomatic treatment and close patient monitoring are the primary therapeutic strategies.
  • Understanding the toxicological profile of honey is crucial for public health advisories.