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Updated: Aug 18, 2026

Measurement of Vacuolar and Cytosolic pH In Vivo in Yeast Cell Suspensions
Published on: April 19, 2013
Sterol homeostasis in the budding yeast, Saccharomyces cerevisiae
Annette L Henneberry1, Stephen L Sturley
1Institute of Human Nutrition, Columbia University Medical Center, New York, NY 10032, USA.
Abstract:
Lipid related diseases, such as obesity, type 2 diabetes, and atherosclerosis are epidemics in developed civilizations. A common underlying factor among these syndromes is excessive subcellular accumulation of lipids such as cholesterol and triglyceride. The homeostatic events that govern these metabolites are understood to varying degrees of sophistication. We describe here the utilization of a genetically powerful model organism, budding yeast, to identify and characterize novel aspects of sterol and lipid homeostasis.
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