Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A particle track-repeating algorithm for proton beam dose calculation.

J S Li1, B Shahine, E Fourkal

  • 1Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. jinsheng.li@fccc.edu

Physics in Medicine and Biology
|March 31, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precise Measurement of the Chromoelectric Dipole Moment of the Charm Quark.

Physical review letters·2026
Same author

Precise Measurement of Matter-Antimatter Asymmetry with Entangled Hyperon-Antihyperon Pairs.

Physical review letters·2026
Same author

[Analysis of the efficacy of half-dose venetoclax combined with reduced-dose HA regimen in the induction therapy of acute myeloid leukemia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2026
Same author

Observation of Λ[over ¯]p→K^{+}π^{+}π^{-}π^{0} and Λ[over ¯]p→K^{+}π^{+}π^{-}2π^{0}.

Physical review letters·2026
Same author

First Measurement of the D_{s}^{+}→K^{0}μ^{+}ν_{μ} Decay.

Physical review letters·2026
Same author

Observation of the Electromagnetic Radiative Decays of the Λ(1520) and Λ(1690) to γΣ^{0}.

Physical review letters·2026
Same journal

Effective contrast-enhanced preprocessing for intracranial artery segmentation in digital subtraction angiography.

Physics in medicine and biology·2026
Same journal

Improving Plan Quality in Adaptive Proton Therapy Using an Interactive Dose Modification Tool.

Physics in medicine and biology·2026
Same journal

Technical Note: Real-Time MLC Control and Latency Measurement Optimization with External Verification.

Physics in medicine and biology·2026
Same journal

Fetus-Specific Hematopoietic Stem Cell Dosimetry Framework for Leukemia-Relevant Target Cells During Prenatal Development.

Physics in medicine and biology·2026
Same journal

Deep learning-based dose prediction to enhance planning efficiency in cervical brachytherapy with hybrid applicators.

Physics in medicine and biology·2026
Same journal

Corrigendum: Referenceless MR thermometry-a comparison of five methods (2017<i>Phys. Med. Biol</i>.<b>62</b>1-16).

Physics in medicine and biology·2026
See all related articles

A new particle track-repeating algorithm significantly speeds up proton beam dose calculations for radiotherapy. This method achieves high accuracy (within 2%) compared to traditional Monte Carlo simulations, making it efficient for clinical applications.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Computational Science

Background:

  • Accurate dose calculation is crucial for effective proton beam radiotherapy.
  • Current Monte Carlo methods (like GEANT3) are computationally intensive, limiting clinical workflow.
  • A faster, accurate algorithm is needed for real-time or near-real-time dose assessment.

Purpose of the Study:

  • To develop and validate a novel particle track-repeating algorithm for rapid proton beam dose calculation.
  • To improve computational efficiency in proton therapy dose planning.
  • To assess the accuracy of the new algorithm against established Monte Carlo simulations.

Main Methods:

  • Simulated monoenergetic 250 MeV protons in water using GEANT3, recording track data.

Related Experiment Videos

  • Developed a track-repeating algorithm to simulate proton transport in patient CT-derived geometries (air, soft tissue, bone).
  • Adjusted particle step lengths and scattering angles based on material density and stopping power, while keeping energy deposition constant.

    • Main Results:

    • The algorithm accurately reproduced dose distributions, with differences within 2% compared to GEANT3 simulations for various proton beam energies (120-250 MeV).
    • Achieved significant speed improvements: ~13x faster for uniform phantoms and >700x faster for heterogeneous phantoms.
    • The algorithm effectively simulated proton beams by adjusting tracks based on incident energy and material properties.

    Conclusions:

    • The particle track-repeating algorithm offers a computationally efficient and accurate alternative for proton beam dose calculation in radiotherapy.
    • This method has the potential to accelerate treatment planning and improve the clinical applicability of proton therapy.
    • Further validation in more complex clinical scenarios is warranted.