[Rheumatological manifestations associated with myelodysplastic and myeloproliferative syndromes]

In 8 patients, an inflammatory polyarthropathy simulating rhizomelic pseudo-rheumatoid arthritis or early RA was the presenting feature of a myeloproliferative or myelodysplasic syndrome. Clinical, radiological, joint cytology and synovial histology findings are analysed. They suggested a link between joint and hematological disorders. Eleven similar cases were found in the literature. The pathophysiological mechanisms are discussed. Anemia, thrombocythemia and excessive monocytosis may be suggestive of myelodysplasia, in particular if the onset of the inflammatory rheumatic disorder is atypical.