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Updated: Aug 18, 2026

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
[Malignant recurrence of a penile cutaneous horn]
Nicolás Alberto Cruz Guerra1, Javier Sáenz Medina, Inmaculada Ursúa Sarmiento
1Servicio de Urología, y de Anatomía Patológica, Complejo Hospitalario de Zamora, Zamora, España.
Objectives:
To report one case of malignant recurrence of a cutaneous horn of the glans penis.
Methods:
We report the case of a 66-year-old male patient presenting with penile discomfort over several months. Physical examination showed a corneal lesion in the glans-penis, the biopsy of which was reported as hyperkeratosis on top of pseudoepiteliomatous hyperplasia. Partial penectomy of the glans penis was performed after recurrence three months later.
Results:
Pathological study of the specimen identified a microinvasive squamous cell carcinoma in the base of the lesion. The patient is disease-free after two years of follow-up.
Conclusions:
We emphasize the capacity the penile cutaneous horn has to become malignant. We also point out the need for observation of these lesions after excision.
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