[Cognitive and behavioural alterations as adverse reaction to tamsulosin not previously described]

To report one case of adverse reaction to tamsulosin.

We describe the case of an 80-year-old patient who was started on alpha blocker treatment after acute urinary retention with the aim to perform a voiding test.

The patient presented self-limited episodes of disorientation in time and space and abnormal behaviour in coincidence with the first three administrations of the drug. Treatment was stopped.

We report one case of an adverse reaction to tamsulosin not previously described. We make a reference to the drug vigilance mechanisms. We point out the importance of coordination between health-care levels.