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Extramammary Paget's disease of scrotum. A case with local lymph node metastasis
David Parada1, Otto Moreira, Carmen López
1Service of Pathology, Vargas Hospital, Caracas, Venezuela. parada@cantv.net
Objective:
We describe the clinical, histological and immunohistochemical studies in a case of extramammary Paget's disease localized in the scrotum with lymph node inguinal metastasis.
Methods/Results:
A 80-year old man consulted with a one-year history of a pruritic erythematous skin rash of the scrotum. Physical examination showed demarcated erythematous lesion involving the scrotum and right inguinal adenopathy. Final histological examination revealed extramammary Paget's disease with inguinal metastasis.
Conclusion:
Extramammary Paget's disease of the scrotum is a rare disease. This pathological condition may spread to dermal region and the regional lymph nodes. Although genitourinary cancer may accompany scrotal extramammary Paget's disease, an extensive search for cancer may be unnecessary.